China Tolterodine Tartrate ụlọ ọrụ na ndị nrụpụta

Tolterodine Tartrate

Nkọwa nkenke:

Appearance White or almost white crystalline powder ,odourless. Solubility Sparingly soluble in methonal, slightly soluble inwater, pratically insoluble in chloroform Melting point 205~ 2 10 ºC ,decomposed during the melting process Specific rotation + 27.0º~+ 30.0º Identification Chemical reaction Solution appears purpureal Characteristic absorption Exhibits a maximum at 282nm IR The IR absorption spectrum of tolterodin tartrate should concordant with that (IR Album N...

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Ngwaahịa

Ọdịdị	White ma ọ bụ nke fọrọ nke nta na-acha ọcha crystalline ntụ ntụ, odorless.
Solubility	Na-etinye obere soluble na methonal, nke nwere ike ịgbanye mmiri na mmiri, na-adịghị edozi mmiri na chloroform
Ebe mgbaze	205 ~ 2 10 ºC, decomposed n'oge usoro agbaze
Ntughari a kapịrị ọnụ	+ 27.0º ~ + 30.0º
IRmata
Chemical mmeghachi omume	Ngwọta na-egosi na ọ dị ọcha
Njirimara njirimara	Na-egosiputa ihe kachasị na 282nm
IR	Igwe ikuku IR nke tolterodin tartrate kwesiri ikwenye na nke ahu (IR Album No.1037) nke ihe omuma
Nzaghachi ọla ọcha nke tartrate	Tinye amonia mmiri mmiri na ọlaọcha nitrat ọtụtụ tụlee, tinye ya na mmiri saa andheat, ọlaọcha dissociates na attaches na ụzọ nke mgbidi nke tube, a ọlaọcha mirror ụdị
Ule
Acidity	PH: 3.0-4.5
Lhloride	Ekwesighi iwe karia ntughari aka site na iji 2.0ml nke onodu sodium chloride (0.025%)
Sọlide	Ekwesighi iwe karia ntunye aka site na iji 1.0ml nke potassium sulphate standard solution (0.05%)
Laevo isomer	NMT1.0%
Ihe ndị metụtara ya	Ọdịdị ọ bụla ọzọ: NMT0.1%
	Total adịghị: NMT 0.5%
Ọrụ	Tolterodine bụ onye na-asọ mpi M na-emegide onye na-emegide ya, na nhọpụta ya na eriri afo siri ike karịa nke mmiri gwọ mmiri. Ya mgbochi nke eriri afo contraction bụ ihe dị ka ugboro 20 nke nke asọ mmiri. Mgbe nchịkwa nke tolterodine, isi ihe na-arụ ọrụ nke 5-hydroxymethyl derivative (DD01) nke imeju mepụtara yiri nke ọrụ antimuscarinic nne na nna ma nwee ọgwụgwọ dị mkpa. Ha abụọ nwere ntakịrị njikọ maka ndị na-anabata ihe ntanetị ndị ọzọ na ndị nwere ike ịchọta ihe gbasara mkpụrụ ndụ dị ka ọwa calcium.