China Tolterodine Tartrate fakitale ndi opanga

Tolterodine Tartrate

Kufotokozera Kwachidule:

Appearance White or almost white crystalline powder ,odourless. Solubility Sparingly soluble in methonal, slightly soluble inwater, pratically insoluble in chloroform Melting point 205~ 2 10 ºC ,decomposed during the melting process Specific rotation + 27.0º~+ 30.0º Identification Chemical reaction Solution appears purpureal Characteristic absorption Exhibits a maximum at 282nm IR The IR absorption spectrum of tolterodin tartrate should concordant with that (IR Album N...

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Mankhwala Mwatsatanetsatane

Zogulitsa

Maonekedwe	White kapena pafupifupi woyera crystalline ufa, odorless.
Kusungunuka	Kusungunuka pang'ono pamadzi, osungunuka pang'ono m'madzi, osasungunuka mu chloroform
Kusungunuka	205 ~ 2 10 ºC, yowonongeka panthawi yosungunuka
Kasinthasintha enieni	+ 27.0º ~ + 30.0º
Chizindikiritso
Mankhwala amachitidwe	Njira yothetsera vutoli imawonekera mwadala
Khalidwe mayamwidwe	Zimaonetsa pazipita pa 282nm
IR	Kutulutsa kwa IR tolterodin tartrate kuyenera kugwirizana ndi (IR Album No. 1037) ya chinthu chofotokozera
Magalasi a siliva amatengera tartrate	Onjezerani ammonia wamadzimadzi okhala ndi siliva osapitilira madontho, ayikeni m'malo osambira amadzi, siliva amasungunuka ndikumamatira kukhoma lamkati la chubu, mawonekedwe agalasi lasiliva
Mayeso
Acidity	PH: 3.0-4.5
Mankhwala enaake	Sayenera kulimbikira kuposa kulongosola pogwiritsa ntchito 2.0ml wa sodium chloride standard solution (0.025%)
Sulfate	Sayenera kulimbikira kuposa kusanthula pogwiritsa ntchito 1.0ml ya potaziyamu sulphate standard solution (0.05%)
Wosangalatsa wa Laevo	NMT1.0%
Zinthu zogwirizana	Chodetsa china chilichonse: NMT0.1%
	Zosowa zonse: NMT 0,5%
Ntchito	Tolterodine ndi mpikisano wampikisano wa M wolandila, ndipo kusankha kwake kwa chikhodzodzo kumakhala kwamphamvu kwambiri kuposa kwam'matumbo. Kuletsa kwake kwa chikhodzodzo cha chikhodzodzo kumakhala pafupifupi nthawi 20 zakumero kwamate. Pambuyo poyendetsa pakamwa tolterodine, chimake chachikulu cha metabolite 5-hydroxymethyl derivative (DD01) chopangidwa ndi chiwindi chimafanana ndi zomwe makolo amachita antimuscarinic ndipo ali ndi tanthauzo lofunikira lakuchiritsa. Onsewa sagwirizana kwenikweni ndi ma neurotransmitter receptors ndi ma cell omwe angakhalepo ngati ma calcium.