China fektheri ea Famotidine le bahlahisi

Famotidine

Tlhaloso e Khutšoanyane:

Appearance White to pale yellowish-white crystalline powder Solubility Freely soluble in dimethylform-amide and in glacial acetic acid; slightly soluble in methanol; very slightly soluble in water; practically insoluble in acetone, in alcohol, in chloroform, in ether, and in ethyl acetate. Identification IR Absorption: Consist with the spectra obtained with Famotidine CRS. Related Substance Related compound B ≤0.3% Related compound C ≤0.3% Related compound D ≤0.3% Re...

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Lihlahisoa tsa Product

Ponahalo	Bosoeu bo bosehla bo bosehla bo bosehla ba kristale e tšoeu
Ho qhibiliha	E qhibiliha ka bolokolohi ka dimethylform-amide le ka glacial acetic acid; qhibilihang hanyane methanol; qhibilihang hanyenyane haholo ka metsing; e ke keng ea qhibiliha ka har'a acetone, joala, chloroform, ether le ethyl acetate.
Boitsebiso	Ire Absorption:
Boitsebiso	E tsamaisana le mokoloko o fumanoeng le Famotidine CRS.
Lintho tse amanang	Motsoako o amanang oa B ≤0.3%
	Motsoako o amanang oa C ≤0.3%
	Motsoako o amanang oa D -0.3%
	Amanang le komponeng E -0.3%
	Motsoako o amanang oa F -0.1%
	Cyanoamidine ≤0.2%
	Amidine ≤0.2%
	Ho se hloeke ho fe kapa hofe ka bomong ≤0.1%
	Kakaretso ea ho se hloeke
Tahlehelo ka ho omisa	.50.5%
Masalla ka thothetsang molelo	.10.1%
Lisebelisoa tse boima	10ppm
Li-solvent tse setseng	Ethanol≤0.5%
Li-solvent tse setseng	Acetone≤0.5%
Hlahloba	.598.5%
Mosebetsi	E na le reng ea thiazole mme e na le tšusumetso e matla ho thibelo ea asiti ea ka mpeng. Nako ea ts'ebetso ke e telele ka ho fetisisa sehlopheng sena sa lithethefatsi. Ha ho na anti-androgen le thibelo ea li-enzyme tsa metabolism. Famotidine e ka thibela phokotso ea likahare tsa glycoprotein ka mpeng ea likhoto tse bakoang ke khatello ea maikutlo, mme taolo e tsoelang pele e ka khothaletsa pholiso ea liso tse sa foleng. Liteko tse fapaneng tse sa boneng tse peli tsa liteko tsa liphoofolo le ho tsoa mali ka mpeng ka mpeng li bonts'itse hore famotidine e na le phello e matla. Sehlahisoa sena se boetse se na le tšusumetso ea ho sireletsa liteko tsa "mucosa" tsa "gastric mucosal" le ho eketsa phallo ea mali ea mucosa ea ka mpeng. Sehlahisoa sena ha se fetole sekhahla sa ho ntša mpa, ha se kena-kenane le ts'ebetso ea pancreatic, ha e na teratogenic, carcinogenic, thibelo ea li-enzyme tsa lithethefatsi tsa sebete le thibelo ea androgen.