Famotidine
| Foliga Vaaia | Paʻepaʻe e sesega samasama-paʻepaʻe crystalline efuefu |
| Solubility | Faʻasaʻoloto i le dimethylform-amide ma i le glacial acetic acid; soluble laitiiti i le methanol; matua feololo i le vai; toetoe lava a le mafai ona lafoa i le acetone, i le ava malosi, i le chloroform, i le ether, ma i le ethyl acetate. |
| Faʻailoaina | Mitiia IRI: |
| Faʻatasi ma le mataʻitusi mauaina ma Famotidine CRS. | |
| Mataupu Fesoasoani | Fesootaiga tuufaatasi B ≤0.3% |
| Fesootaiga tuʻufaʻatasi C ≤0.3% | |
| Fesootaiga tuʻufaʻatasiga D ≤0.3% | |
| Fesootaiga tuʻufaʻatasiga E ≤0.3% | |
| Fesootaiga tuʻufaʻatasi F ≤0.1% | |
| Cyanoamidine ≤0.2% | |
| Amidine ≤0.2% | |
| Soʻo seisi lava amioga le mama a le tagata ≤0.1% | |
| Aofaʻiga l≤ mama≤ 1.0% | |
| Maliu i le Faʻamamago | ≤0.5% |
| .Residue i le afi | ≤0.1% |
| Uamea mamafa | ≤10ppm |
| Faʻavaʻa solvents | Ethanol≤0.5% |
| Acetone≤0.5% | |
| Tofotofo | ≥98.5% |
| Galuega tauave | O loʻo iai le mama a le thiazole ma e iai lona malosi e taofiofi ai le faʻamalama o le gastric acid. Ole umi ole gaioiga e sili ona umi ile vasega lea o vailaʻau. Leai se anti-androgen ma le taofiofia o metabolic enzymes. Famotidine mafai mafai tele taofia le faʻaititia o glycoprotein mataupu i le gastric mucosa o isumu faaosoina e le popole, ma faifai pea pulega mafai ona faʻamalosia le faʻamaloloina o masani papala. Faʻalua-tauaso faʻatusatusaga faʻataʻitaʻiga i manu faʻataʻitaʻiga ma falemaʻi pito i luga gastrointestinal toto ua faʻaalia ai o le famotidine ei ai lona hemostatic aafiaga. Lenei oloa i ai foi le aʻafiaga o le puipuia faʻataʻitaʻi gastric mucosal faʻaleagaina ma faʻateleina le tafe o le toto o gastric mucosa. Lenei oloa e le suia le fua faatatau o gastric gaogao, e le faʻalavelave i pancreatic gaioiga, leai teratogenic, carcinogenic, taofia o ate ate fualaʻau ma le taofiofia o androgen. |
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