Famotidine
| Te Ahua | Ma ki te ma kowhai-ma kowhai-paura karaihe paura |
| Te wairewa | He waatea noa i te dimethylform-amide me te waikawa acetic glacial; paku wairewa i roto i te methanol; tino wairewa i roto i te wai; kaore e taea te rewa i roto i te acetone, i te waipiro, i te chloroform, i te ether, me i te ethyl acetate. |
| Tuakiri | Ngongo IR: |
| Whakauru atu ki te mahinga miiharo i whakawhiwhia ki te Famotidine CRS. | |
| Matū e Hono ana | Pūhui hono B ≤0.3% |
| Pūhui hono C ≤0.3% | |
| Pūhui hono D ≤0.3% | |
| Pūhui e hono ana ≤0.3% | |
| Pūhui hono F ≤0.1% | |
| Cyanoamidine ≤0.2% | |
| Amidine ≤0.2% | |
| Tetahi atu poke takitahi individual0.1% | |
| Mahinga katoa≤ 1.0% | |
| Ngaronga o te maroke | ≤0.5% |
| Tuhinga o mua | ≤0.1% |
| Konganuku taumaha | ≤10ppm |
| Nga wairewa toenga | Ethanol≤0.5% |
| Acetone≤0.5% | |
| Whakamatautau | ≥98.5% |
| Mahi | Kei roto he mowhiti thiazole a he kaha te aukati i te rerenga o te waikawa puku. Ko te roa o te mahi ko te roa rawa atu i tenei akomanga o nga raau taero. Kaore he anti-androgen me te aukati i nga haurangi haurangi. Ka taea e te Famotidine te aukati i te whakahekenga o te ihirangi glycoprotein i roto i te puku haumanu o te kiore e ahu mai ana i te ahotea, ma te whakahaere tonu ka taea te whakatairanga i te whakaora o nga kaahi kawa. Ko nga whakamatautau rereke-matapo i nga whakamatautau kararehe me te haumanu o te puku o te puku kua whakaatuhia he nui te kaha o te famotidine. Ko tenei hua he paanga mo te tiaki i te kino o te mucosal gastric me te whakanui ake i te rere o te toto o te mucosa gastric. Kaore tenei hua e whakarereke i te tere o te putunga o te kopu, kaore e raweke ki te mahi a te pancreatic, kaore he teratogenike, he mate pukupuku, he aukati i nga whiu rongoa ate me te aukati i te androgen. |
Tuhia to korero ki konei ka tuku mai ki a maatau
