Tuam Tshoj Famotidine Hoobkas thiab tuam ntxhab

Famotidine

Cov lus piav qhia luv luv:

Appearance White to pale yellowish-white crystalline powder Solubility Freely soluble in dimethylform-amide and in glacial acetic acid; slightly soluble in methanol; very slightly soluble in water; practically insoluble in acetone, in alcohol, in chloroform, in ether, and in ethyl acetate. Identification IR Absorption: Consist with the spectra obtained with Famotidine CRS. Related Substance Related compound B ≤0.3% Related compound C ≤0.3% Related compound D ≤0.3% Re...

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Khoom Nthuav dav

Cov khoom lag luam

Tsos	Dawb kom daj ntseg daj-dawb crystalline hmoov
Tub sab	Yoog soluble nyob rau hauv dimethylform-amide thiab hauv glacial acetic acid; soluble me ntsis hauv methanol; heev me ntsis soluble hauv dej; xyaum insoluble hauv acetone, haus dej cawv, hauv chloroform, hauv ether, thiab ethyl acetate.
Kev Qhia Txog	IR Kev Zam:
Kev Qhia Txog	Suav nrog lub tsom iav tau nrog Famotidine CRS.
Lwm Yam Khoom	Cov kev sib xyaw ua ke B .30.3%
	Yam sib cuam tshuam C ≤0.3%
	Lwm cov sib txuas D ≤0.3%
	Lwm cov sib xyaw tiv thaiv E ≤0.3%
	Cov kev sib xyaw ua ke F ≤0.1%
	Cyanoamidine ≤0.2%
	Amidine ≤0.2%
	Ib qho ntawm lwm tus neeg impurity ≤0.1%
	Tag nrho impurity≤ 1.0%
Poob Rau Kom Qhuav	0.5%
.Residue ntawm Kev Tshawb Fawb	≤0.1%
Cov hlau hnyav	10ppm
Cov kuab tshuaj nyob zoo	Ethanol≤0.5%
Cov kuab tshuaj nyob zoo	Acetone≤0.5%
Ntsuas	≥98.5%
Muaj nuj nqi	Nws muaj lub nplhaib thiazole thiab muaj lub zog ua kom muaj zog ntawm lub plab hnyuv ntxig. Lub sijhawm tiv thaiv yog qhov ntev tshaj plaws hauv chav kawm ntawm cov tshuaj no. Tsis muaj anti-androgen thiab inhibition ntawm cov enzymes metabolic. Famotidine tuaj yeem cuam tshuam qhov kev txo qis ntawm glycoprotein cov ntsiab lus nyob rau hauv lub plab zom mov ntawm nas los ntawm kev ntxhov siab, thiab kev tswj hwm tas mus li tuaj yeem txhawb txoj kev kho mob ntawm mob txhab. Muab ob zaug dig muag sib piv hauv kev sim tsiaj thiab kev kho lub plab zom mov sab saud tau ua pov thawj tias famotidine muaj cov kab mob hemostatic. Cov khoom no tseem muaj qhov ua haujlwm tiv thaiv kev mob plab hnyuv thiab ua kom ntshav khiav ntawm lub plab hnyuv. Cov khoom no tsis hloov pauv ntawm lub plab zom mov, tsis cuam tshuam rau lub luag haujlwm ntawm tus kabmob ua haujlwm, tsis muaj teratogenic, carcinogenic, inhibition ntawm daim siab tshuaj enzymes thiab inhibition ntawm androgen.