Rifampicin (Rifaximin), inotora rifamycin, yakagadzirwa naAlfa Italy. Yakatengeswa muItari semushonga unorwisa hutachiona wemanyoka muna 1987 uye uchiri kushandiswa zvakanyanya kunze kwenyika. Yakagamuchirwa neSFDA mu2004, yanga ichishandiswa mune zvekurapa muChina. Iyo semi-synthetic antibacterial drug ye rifamycin. Iyo ine yakafara antibacterial spectrum uye yakasimba antibacterial chiitiko. Inogona kuumba yakakwira kuwanda kweropa mumatumbu turakiti. Inogona kutadzisa Staphylococcus aureus, Streptococcus faecalis uye Salmonella mu gram-positive maaerobes, ayo ari ejenasi Salmonella muGram-negative aerobic bacteria. Shigella naEscherichia coli, Yersinia enterocolitica uye Gram-positive anaerobic mabhakitiriya vese vane yakanyanya antibacterial chiitiko. Iyo mashandiro ekuita kwayo ndeyekudzivirira bhakitiriya polymerase, kuvharira chirongwa cheRNA, uyezve kudzvinyirira synthesis yebhakitiriya protein, nekudaro ichideredza kugadzirwa kweammonia. 1) chiitiko che antibacterial chakasimba, uye iyo antibacterial spectrum yakafara. Iyo ine bactericidal athari kune akawanda gram-akanaka mabhakitiriya uye gram-isina mabhakitiriya (anosanganisira mabhakitiriya eerobic uye anaerobic mabhakitiriya), uye mhedzisiro pane gram-yakanaka mabhakitiriya akasimba kupfuura ayo pane gram-isina mabhakitiriya. 2) haina kunyudzwa nemudumbu, uye iko kusungwa kwayo kwakanyanya mudumbu. Inogona kuuraya utachiona hwemuviri uye inotamba inorwisa mabhakitiriya nekukurumidza munzvimbo yemuno, uye hazvidiwe kushandisa antispasmodic uye adsorptive zvinodhaka pamwe chete nemudumbu.