Rifampicin (Rifaximin), e tsoang ho rifamycin, e entsoe ke Alfa Italy. E ile ea rekisoa Italy e le sethibela-mafu se thibelang tšoaetso ho 1987 mme e ntse e sebelisoa haholo kantle ho naha. E amohetsoe ke SFDA ka 2004, e sebelisitsoe litloaelong tsa bongaka Chaena. Ke sehlahisoa sa anti-antibacterial ea semi-synthetic ea rifamycin. E na le tšebetso e pharaletseng ea li-antibacterial le ts'ebetso e matla ea li-antibacteria. E ka theha mali a mangata haholo maling. E ka thibela Staphylococcus aureus, Streptococcus faecalis le Salmonella ka li-aerobes tse nang le gram-positive, tseo e leng tsa mofuta oa Salmonella ka libaktheria tsa Gram-negative aerobic. Shigella le Escherichia coli, Yersinia enterocolitica le Gram-positive anaerobic bacteria kaofela ba na le diketsahalo tse phahameng tsa ho thibela dikokwanahloko. Mechini ea ts'ebetso ea eona ke ho thibela baktheria polymerase, ho thibela ts'ebetso ea phetolelo ea RNA, ebe e thibela tšebetso ea protheine ea baktheria, ka hona e fokotsa tlhahiso ea ammonia. 1) tšebetso ea ho thibela likokoana-hloko e matla, 'me sebakanyana sa antibacteria se pharalletse. E na le phello ea baktheria ho libaktheria tse ngata tse nang le gram le libaktheria tse nang le gram-negative (ho kenyeletsoa libaktheria tsa aerobic le libaktheria tsa anaerobic), mme litlamorao ho libaktheria tse nang le gram li matla ho feta tse libaktheria tse gram-negative. 2) ha e kenngoe ke pampiri ea meno, 'me mohopolo oa eona o phahame haholo ka maleng. E ka bolaea kokoana-hloko ea tšoaetso ea mala mme ea bapala phello e khahlanong le baktheria kapele sebakeng sa lehae, mme ha ho hlokahale ho sebelisa lithethefatsi tsa antispasmodic le adsorptive hammoho le mala a mala.