Rifampicin (Rifaximin), yog ib pawg neeg ntawm rifamycin, tau tsim los ntawm Alfa Ltalis. Nws tau muag hauv Ltalis raws li kev tiv thaiv kev kis mob raws plab hauv xyoo 1987 thiab tseem siv dav dav txawv teb chaws. Pom zoo los ntawm SFDA xyoo 2004, nws tau coj los siv rau hauv chaw kho mob hauv Suav teb. Nws yog cov tshuaj tiv thaiv ib nrab ntawm cov khoom siv ntawm rifamycin. Nws muaj cov kab mob dav dav thiab muaj zog tiv thaiv kev ua haujlwm. Nws tuaj yeem tsim cov qib siab ntawm cov ntshav hauv txoj hnyuv. Nws tuaj yeem inhibit Staphylococcus aureus, Streptococcus faecalis thiab Salmonella ntawm cov tshuaj aerobes zoo, uas yog koom nrog tus kheej Salmonella hauv cov kab mob Gram-negative aerobic. Shigella thiab Escherichia coli, Yersinia enterocolitica thiab cov kab mob Gram-positive anaerobic txhua tus muaj cov tshuaj tiv thaiv kab mob siab. Lub tshuab ntawm nws cov kev ua yog inhibit cov kab mob polymerase, thaiv qhov kev hloov tsheb ntawm RNA, thiab tom qab ntawd inhibit kev sib txuas ntawm cov kab mob protein, yog li txo cov ammonia ntau lawm. 1) cov haujlwm ua tus kabmob muaj zog, thiab cov tshuaj tua kabmob loj yog qhov dav. Nws muaj cov kab mob bactericidal ntawm feem ntau cov kab mob gram-zoo thiab cov kab mob gram-tsis zoo (suav nrog cov kab mob aerobic thiab cov kab mob anaerobic), thiab cov nyhuv ntawm cov kab mob gram-zoo yog muaj zog dua li ntawm cov kab mob gram-negative. 2) nws tsis yog nqus los ntawm txoj hnyuv hauv plab, thiab nws cov concentration ntau heev nyob rau hauv txoj hnyuv. Nws tuaj yeem tua cov kab mob ntawm txoj hnyuv thiab ua si tawm tsam cov kab mob sai sai hauv thaj chaw hauv zos, thiab nws tsis tas yuav siv cov tshuaj antispasmodic thiab adsorptive los ua ke nrog txoj hnyuv.