Ko te Huaora C, e mohiotia ana ko te waikawa ascorbic, he tino kai-wairewa-wairewa. Ko nga taangata me etahi atu kararehe (penei i te timatanga, poaka) ka whakawhirinaki ki te huaora C kei roto i nga kai me nga huawhenua (pepa whero, karaka, rōpere, broccoli, manga, rēmana). Ko te kaha pea o te huaora C ki te aukati me te whakapai ake i nga mate kua kitea i roto i te hapori hauora.
Ko te waikawa Asborbic he mea nui hei whakautu urupare. He mea nui ki te aukati, ki te whakaora i te mate totokore, ki te waikawa, ki te anti-thrombosis me nga taonga anti-viral.
Vitamin C seems to be able to regulate the host's response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus is the causative factor of the 2019 coronavirus disease (COVID-19) pandemic, especially It is in a critical period. In a recent comment published in Preprints*, Patrick Holford et al. Solved the role of vitamin C as an auxiliary treatment for respiratory infections, sepsis and COVID-19.
Ko tenei tuhinga e korero ana mo te kaha pea o te huaora C ki te aukati i te waahanga nui o te COVID-19, nga mate whakapehapeha kaha me etahi atu mate mumura. Ko te taapiri o te Huaora C e kiia ana he kaitautoko, he rongoa whakaora ranei mo te COVID-19-ki te whakatika i nga ngoikoretanga i pangia e te mate, te whakaiti i te ahotea o te waikawa, te whakarei ake i te mahi interferon me te tautoko i nga hua anti-mumura o te glucocorticoids.
Hei pupuri i nga taumata plasma noa i nga pakeke i te 50 µmol / l, ko te inenga huaora C mo nga tane ko te 90 mg / d me nga waahine 80 mg / d. He nui tenei hei aukati i te kopurehu (he mate na te kore o te huaora C). Heoi, kaore i te rawaka tenei taumata hei aukati i te parekura o te viral me te taumaha o te tinana.
Therefore, the Swiss Nutrition Society recommends supplementing each person with 200 mg of vitamin C-to fill the nutritional gap of the general population, especially adults 65 years and older. This supplement is designed to strengthen the immune system. "
I raro i nga tikanga ahuru o te koiora, ka heke te tere o te haurangi waikawa C tangata. Ko te rongoa huaora C kei roto i nga turoro i te hohipera he ≤11µmol / l, a ko te nuinga o ratau e pangia ana e te mate o te manawa romahā, sepsis te COVID-19 nui rawa atu.
I roto i nga momo rangahau puta noa i te ao, he iti te taumata o te huaora C kei roto i nga tuuroro e pangia ana e te mate turoro, te niumonia, te sepsis me te COVID-19-ko te whakamaarama pea ko te whakapiki i te kai pūkoro.
Ko te taatai-taatai ​​i whakaatu i nga kitenga e whai ake nei: 1) Ko te taapiri o te Huaora C ka kaha ki te whakaiti i te tuponotanga o te niumonia, 2) Ko nga tirotiro tirotiro tuuroro i muri i te matenga o te COVID-19 i whakaatu i te niumonia tuarua, me te 3) Ko te ngoikoretanga o te Huaora C i kiia mo te katoa o te iwi pūkahukahu 62%.
Ko te Huaora C he painga nui ki te kaainga hei antioxidant. E mohiotia ana he mahi patu wheori tika a ka taea te whakanui ake i te hanga interferon. Kei i a ia nga kaitautoko aarai i roto i nga punaha aarai mate taiao me te urutau. Ko te Huaora C te whakaheke i nga momo hāora urupare (ROS) me te mumura ma te whakaheke i te whakahohenga o te NF-κB.
SARS-CoV-2 down-regulates the expression of type 1 interferon (the host's main antiviral defense mechanism), while ascorbic acid up-regulates these key host defense proteins.
Ko te waahanga nui o te COVID-19 (ko te waa te waahanga mate) ka puta i te wa e kaha ana te whakaputa i nga cytokine pro-inflammatory me nga chemokines. Na tenei i whanakehia ai te maha o nga ngoikoretanga o te okana. E pa ana ki te heke me te kohi o nga neutrophil i roto i te pungahuru interstitium me te kohao bronchoalveolar, ko te mea nui tenei hei tohu matua mo te ARDS (Acute Respiratory Distress Syndrome).
Ko te kukume o te waikawa ascorbic i roto i nga repe adrenal me te repe pituitary he toru ki te tekau nga wa neke atu i era atu okana. I raro i te ahotea o te koiora (whakaohooho ACTH) nga tikanga tae atu ki te huaketo viral, ka tukuna te huaora C mai i te uha adrenal, kia piki ai te reima o te plasma.
Ka taea e te Huaora C te whakarei ake i te hanga o te cortisol, me te whakarei ake i te aukati anti-mumura me te endothelial hei painga paruru o te glucocorticoids. Ko nga taatai ​​Exogenous glucocorticoid anake nga raau taero i whakamatauhia hei whakaora COVID-19. Ko te Huaora C he homoni whakaohooho-a-tini, he mea nui ki te takawaenga i te uruparotanga o te uho adrenal (ina koa te sepsis) me te tiaki i te endothelium mai i te kino o te waikura.
Ma te whakaaro ki te hua o te huaora C ki nga makariri-ka whakaheke i te roanga, te kaha me te auau o te makariri-tango huaora C ka taea te whakaiti i te whakawhiti mai i te mate ngawari ki te waa whakahirahira o te COVID-19.
Kua kitea ka taea e te taapiringa huaora C te whakapoto i te roa o te noho ki te ICU, te whakapoto i te waa haangai o nga tuuroro tuuroro me te COVID-19, me te whakaheke i te tatauranga matemate o nga tuuroro sepsis e hiahia ana kia rongoa me nga kaimakimakawe.
Ma te whakaaro ki nga momo mate koretake, kohatu kowhatu me te ngoikoretanga o te tarai i te waa nui, ka korerohia e nga Kaituhi te ahuru o te whakahaere waha-a-waha o te huaora C. Ka taea te taunaki he horopeta poto poto-2-8 g / ra ( kia tupato karo i nga toketa teitei mo nga taangata he hitori o te kohatu tarai, mate maakuku ranei). Na te mea he wairewa-i te wai, ka taea te whakaputa i roto i etahi haora, no reira he mea nui te auau inenga ki te pupuri i te toto totika i te wa e pangia ana e te mate.
E mohio katoa ana taatau, ka taea e te huaora C te aukati i te mate me te whakapai ake i te urupare aukati. Ina koa e pa ana ki te waahanga whakahirahira o te COVID-19, ko te huaora C te mea nui. Ka whakatauhia-e ia te tupuhi cytokine, ka tiakina te endothelium mai i te kino o te waikura, he mea nui ki te whakatika kiko, me te whakapai ake i te urupare aukati ki te mate.
Ka taunaki te kaituhi kia tapirihia nga taapiringa huaora C i nga ra katoa hei akiaki i nga roopu morearea me te nui o te mate a te COVID-19 me te ngoikore o te huaora C. Me whakarite tonu e ratau ko te huaora C me te whakanui ake i te horopeta ka pangia te mate huaketo, tae atu ki te 6-8 g / ra. Kei te haere tonu te maha o nga rangahau roopu huaora C-haumanu-a-koiora ki te whakatutukitanga i tana mahi ki te whakaora i te COVID-19 me te maarama pai ki tana mahi hei kaha whakaora.
Ka whakaputahia e te Panui nga purongo aiao timatanga kaore ano kia arotakehia e nga hoa, no reira kaua e kiia he whakatau, hei arahi i nga mahi haumanu / whanonga e pa ana ki te hauora, ki nga korero pono ranei.
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Ramya he PhD. I whakawhiwhia te Pune National Chemical Laboratory (CSIR-NCL) ki te PhD i roto i te Biotechnology. Kei roto i ana mahi nga nanoparticles mahi me nga momo ngota ngota koiora koiora, te ako i nga punaha urupare me te hanga tono whaihua.
Dwivedi, Ramya. (2020, Oketopa 23). Huaora C me COVID-19: He arotake. News rongoa. I tangohia mai i https://www.news-medical.net/news/20201023/Vitamin-C-and-COVID-19-A-Review.aspx i te Whiringa-a-Rangi 12, 2020.
Dwivedi, Ramya. "Vitamin C and COVID-19: A Review." News medical. November 12, 2020. .
Dwivedi, Ramya. "Vitamin C and COVID-19: A Review." News medical. https://www.news-medical.net/news/20201023/Vitamin-C-and-COVID-19-A-Review.aspx. (Accessed on November 12, 2020).
Dwivedi, Ramya. 2020. "Vitamin C and COVID-19: A Review." News-Medical, browsed on November 12, 2020, https://www.news-medical.net/news/20201023/Vitamin-C-and-COVID-19-A-Review.aspx.
I roto i tenei uiui, i whakaputahia e Ahorangi Paul Tesar me Kevin Allan nga purongo ki nga puka rongoa rongo mo te iti o te kaha o te hāora e pakaru te roro.
I roto i tenei uiui, i korero a Dr. Jiang Yigang mo te ACROBiosystems me tana kaha ki te whawhai ki te COVID-19 me te rapu kano kano
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News-Medical.Net e whakarato ana i tenei ratonga korero hauora kia rite ki enei tikanga me nga tikanga. Kia mahara ko nga korero hauora i kitea i runga i tenei paetukutuku ka whakamahia noa hei tautoko, kaua hei whakakapi i te hononga i waenga i nga tuuroro me nga taote me nga tohutohu hauora ka taea e raatau.
Ka whakamahia e matou nga pihikete hei whakarei i to wheako. Ma te tirotiro tonu i tenei paetukutuku, ka whakaae koe ki ta maatau whakamahi pihikete. He korero ano.