Vitamin C, wanda aka fi sani da ascorbic acid, muhimmin abinci ne mai narkewa cikin ruwa. Mutane da wasu dabbobin (kamar su birrai, aladu) sun dogara da bitamin C a cikin wadataccen abinci na 'ya'yan itatuwa da kayan marmari (jan barkono, lemu, strawberry, broccoli, mango, lemon). An fahimci tasirin bitamin C wajen hanawa da inganta kamuwa da cuta a cikin ƙungiyar likitocin.
Ascorbic acid yana da mahimmanci don amsawar rigakafi. Yana da mahimmancin kumburi, immunomodulatory, antioxidant, anti-thrombosis da anti-viral virus.
Vitamin C seems to be able to regulate the host's response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus is the causative factor of the 2019 coronavirus disease (COVID-19) pandemic, especially It is in a critical period. In a recent comment published in Preprints*, Patrick Holford et al. Solved the role of vitamin C as an auxiliary treatment for respiratory infections, sepsis and COVID-19.
Wannan labarin yana tattauna tasirin rawar bitamin C wajen hana mawuyacin matakin COVID-19, ƙananan cututtuka na numfashi da sauran cututtukan kumburi. Ana sa ran ƙarin Vitamin C ya zama mai hana rigakafi ko mai ba da magani ga COVID-19-gyara ƙarancin raunin da cutar ta haifar, rage stressarfin ƙwayoyin cuta, haɓaka haɓakar interferon da tallafawa abubuwan da ke haifar da kumburi na glucocorticoids.
Don kiyaye matakan plasma na al'ada a cikin manya a 50 µmol / l, maganin bitamin C ga maza shine 90 mg / d kuma ga mata 80 mg / d. Wannan ya isa ya hana cututtukan fata (cutar da rashin bitamin C ya haifar). Koyaya, wannan matakin bai isa ya hana yaduwar kwayar cuta da damuwa na ilimin lissafi ba.
Therefore, the Swiss Nutrition Society recommends supplementing each person with 200 mg of vitamin C-to fill the nutritional gap of the general population, especially adults 65 years and older. This supplement is designed to strengthen the immune system. "
A karkashin yanayin matsi na ilimin lissafi, sinadarin dan adam bitamin C ya sauka cikin sauri. Maganin bitamin C na marasa lafiya a asibiti shine ≤11µmol / l, kuma mafi yawansu suna fama da mummunan cututtuka na numfashi, sepsis ko COVID-19 mai tsanani.
Nazarin shari'ar daban-daban daga ko'ina cikin duniya ya nuna cewa ƙananan matakan bitamin C sun zama gama gari ga marasa lafiya marasa lafiya marasa lafiya da ke fama da cututtukan numfashi, ciwon huhu, sepsis da COVID-19-mafi yuwuwar bayani shine ƙara yawan amfani da kumburi.
Meta-analysis ya nuna waɗannan abubuwan da aka lura: 1) supplementarin Vitamin C zai iya rage haɗarin ciwon huhu, 2) Binciken bayan mutuwa bayan mutuwa daga COVID-19 ya nuna ciwon huhu na biyu, kuma 3) Rashin Vitamin C ya lissafta yawan mutanen da ciwon huhu 62%.
Vitamin C yana da mahimmin sakamako na gida kamar antioxidant. An san shi yana da aikin kashe kwayar cutar kai tsaye kuma yana iya haɓaka samar da interferon. Yana da hanyoyin haɓaka a cikin tsarin rigakafi na asali da na daidaitawa. Vitamin C yana rage nau'ikan oxygen masu aiki (ROS) da kumburi ta hanyar rage kunnawa na NF-κB.
SARS-CoV-2 down-regulates the expression of type 1 interferon (the host's main antiviral defense mechanism), while ascorbic acid up-regulates these key host defense proteins.
Babban mawuyacin lokaci na COVID-19 (yawanci lokaci mai saurin mutuwa) yana faruwa yayin haɓakar tasirin ƙwayoyin cuta masu saurin kumburi da chemokines. Wannan ya haifar da ci gaban raunin gabobi da yawa. Yana da alaƙa da ƙaura da kuma tarawar ƙwayoyin cuta a cikin masassarar huhu da kogon bronchoalveolar, na biyun shine maɓallin kewayawa na ARDS (Ciwon piwayar piwayar piwayar )wayar Cutar).
Halin da ake samu na ascorbic acid a cikin gland adrenal da kuma pituitary gland ya ninka sau uku zuwa goma fiye da kowane sashin jiki. Arkashin danniya na ilimin lissafi (motsawar ACTH) yanayi gami da bayyanar kwayar cuta, ana fitar da bitamin C daga mahaifa, yana haifar da matakan plasma ya ninka sau biyar.
Vitamin C na iya haɓaka samar da cortisol, da haɓaka haɓakar anti-inflammatory da ƙwayoyin endothelial masu kariya na glucocorticoids. Steroidswayoyin cututtukan cututtukan glucocorticoid sune kawai ƙwayoyi waɗanda aka tabbatar da su kula da COVID-19. Vitamin C shine tasirin motsa jiki mai tasiri mai yawa, wanda ke taka muhimmiyar rawa wajen sasanta yanayin damuwa na damuwa na adrenal cortex (musamman sepsis) da kuma kare endothelium daga lalacewar sanadari.
La'akari da tasirin bitamin C akan mura-rage tsawon lokaci, tsanani da kuma yawan lokacin shan sanyi-shan bitamin C na iya rage sauyawa daga kamuwa da cuta mai sauƙi zuwa mawuyacin lokacin COVID-19.
An lura cewa ƙarin bitamin C na iya rage tsawon lokacin zama a cikin ICU, ya rage lokacin samun iska na marasa lafiyar masu cutar tare da COVID-19, da kuma rage yawan mace-macen masu cutar sepsis waɗanda ke buƙatar magani tare da vasopressors.
La'akari da yanayi daban-daban na gudawa, duwatsun koda da gazawar koda a lokacin allurai masu yawa, marubutan sun tattauna game da amincin sarrafa baki da maganin cikin bitamin C. Ana iya ba da shawarar ƙaramin ƙarfi na ɗan gajeren lokaci na 2-8 g / rana ( a hankali a guji yin allurai masu yawa ga mutanen da ke da tarihin dutsen koda ko cutar koda). Saboda ruwa ne mai narkewa, ana iya fitar da shi cikin yan awanni kaɗan, saboda haka yawan sashi yana da mahimmanci don kiyaye matakan jini sosai yayin kamuwa da cuta.
Kamar yadda muka sani, bitamin C na iya hana kamuwa da cuta da kuma inganta garkuwar jiki. Musamman magana game da mahimmin matakin COVID-19, bitamin C yana da mahimmin rawa. Ya rage-daidaita hadari na cytokine, ya kare endothelium daga lalacewar oxidative, yana taka muhimmiyar rawa wajen gyaran nama, kuma yana inganta rigakafin rigakafin kamuwa da cuta.
Marubucin ya ba da shawarar cewa ya kamata a ƙara abubuwan bitamin C a kowace rana don ƙarfafa ƙungiyoyi masu haɗari tare da yawan mutuwar COVID-19 da ƙarancin bitamin C. Ya kamata koyaushe su tabbatar da cewa bitamin C ya wadatar kuma ya ƙara adadin lokacin da cutar ta kamu, har zuwa 6-8 g / rana. Yawancin karatun ƙungiyar bitamin C masu ɗorewa suna gudana a duk duniya don tabbatar da rawar da take takawa wajen sauƙaƙe COVID-19 kuma don ƙarin fahimtar matsayin ta azaman ikon warkewa.
Masu gabatarwa za su buga rahotanni na farko na kimiyya waɗanda ba a sake duba su ba, sabili da haka bai kamata a yi la'akari da su ba, jagorantar aikin likita / halayyar da suka shafi lafiya ko la'akari da cikakken bayani.
Tags: ciwo mai ciwo mai tsanani, anti-mai kumburi, antioxidant, ascorbic acid, jini, broccoli, chemokine, coronavirus, cutar coronavirus COVID-19, corticosteroid, cortisol, cytokine, cytokine, gudawa, yawanci, Glucocorticoids, hormones, ba da amsa, rigakafi tsarin, kumburi, tsakanin tsakiya, koda, cututtukan koda, gazawar koda, yawan mace-mace, abinci mai gina jiki, gajiya mai yaduwa, annoba, ciwon huhu, numfashi, SARS-CoV-2, scurvy, Sepsis, ciwo mai tsanani na numfashi, mai tsananin ciwo na numfashi, strawberry, damuwa , ciwo, kayan lambu, ƙwayoyin cuta, bitamin C
Ramya yana da PhD. Pune National Laboratory Laboratory (CSIR-NCL) ta sami Digiri na uku a fannin kimiyyar kere kere. Ayyukanta sun hada da sarrafa abubuwa nanoparticles tare da mabanbantan kwayoyin halittar sha'awa, nazarin tsarin daukar hankali da gina aikace-aikace masu amfani.
Dwivedi, Ramya. (2020, Oktoba 23). Vitamin C da COVID-19: Wani bita. Labaran likita. An dawo daga https://www.news-medical.net/news/20201023/Vitamin-C-and-COVID-19-A-Review.aspx a kan Nuwamba 12, 2020.
Dwivedi, Ramya. "Vitamin C and COVID-19: A Review." News medical. November 12, 2020. .
Dwivedi, Ramya. "Vitamin C and COVID-19: A Review." News medical. https://www.news-medical.net/news/20201023/Vitamin-C-and-COVID-19-A-Review.aspx. (Accessed on November 12, 2020).
Dwivedi, Ramya. 2020. "Vitamin C and COVID-19: A Review." News-Medical, browsed on November 12, 2020, https://www.news-medical.net/news/20201023/Vitamin-C-and-COVID-19-A-Review.aspx.
A cikin wannan tattaunawar, Farfesa Paul Tesar da Kevin Allan sun buga labarai ga mujallolin likitanci na labarai game da yadda ƙananan iskar oxygen ke lalata kwakwalwa.
A cikin wannan tattaunawar, Dokta Jiang Yigang ya tattauna game da tsarin ACROBiosystems da kokarin da take yi wajen yakar COVID-19 da kuma neman alluran rigakafi
A wannan tattaunawar, News-Medical sun tattauna kan ci gaban da kuma yanayin kwayar cutar ta monoclonal tare da David Apiyo, babban manajan aikace-aikace a Sartorius AG.
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