Vitamin B 12, also known as cobalt amine, is the only vitamin containing metal elements. In nature, vitamin B12 is synthesized by microorganisms. Higher animals and plants cannot make vitamin B12. Vitamin B12 is the only vitamin that requires the help of an intestinal secretion (endogenous factor) to be absorbed. Some people due to gastrointestinal abnormalities, lack of this endogenous factor, even if adequate dietary sources can also suffer from malignant anemia. There is basically no vitamin B12 in vegetable foods. It stays in the gut for a long time and takes about three hours (most water-soluble vitamins take only a few seconds) to be absorbed. Vitamin B 12's main physiological function is to participate in the production of bone marrow red blood cells, prevent malignant anemia, prevent brain nerve damage. Vitamin B 12 is one of the last B vitamins to be found so far. Vitamin B12 is a polycyclic compound containing 3 valent cobalt. Four reduced pyrrole rings are linked together to form a Golin macroring (similar to porphyrin), which is the core of vitamin B12 molecule. Therefore, compounds containing this ring are referred to as Golin-like. Vitamin B12 is a light red acicular crystal which is easily soluble in water and ethanol. It is most stable under the condition of weak acid pH 4.5 and 5.0, and decomposes in strong acid (pH < 2) or alkaline solution, which can be destroyed to some extent in the event of heat. But short time high temperature disinfection loss is small, encounter bright light or ultraviolet ray is easy to be destroyed. The loss of ordinary cooking process is about 30%.

ຊື່​ຜະ​ລິດ​ຕະ​ພັນ:	VITAMIN 12
CAS:	68-19-9
MF:	C63H88CoN14O14P
MW:	55 1355.3.77
EINECS:	200-680-0
ວິຕາມິນ B12, ເຊິ່ງເອີ້ນວ່າ VB12 ໂດຍຫຍໍ້, ເຊິ່ງເອີ້ນກັນວ່າ cobalamin, ແລະແມ່ນ ໜຶ່ງ ໃນວິຕາມິນ B, ແມ່ນຊັ້ນປະສົມສານອິນຊີທີ່ສັບສົນທີ່ບັນຈຸຫ້ອງຮຽນ Cobrin Corrin, ແລະມີສານ trivalent cobalt ໃນຍົນຄ້າຍຄືກັນຂອງຖ່ານຫີນ Corrin ຢູ່ໃຈກາງວົງ ມັນແມ່ນໂມເລກຸນວິຕາມິນທີ່ໃຫຍ່ທີ່ສຸດແລະສັບສົນທີ່ສຸດທີ່ໄດ້ຄົ້ນພົບ. ມັນຍັງເປັນວິຕາມິນດຽວທີ່ມີທາດໂລຫະທາດເຫຼັກ. ໄປເຊຍແມ່ນສີແດງ, ມັນກໍ່ຖືກເອີ້ນວ່າວິຕາມິນສີແດງ. ພືດບໍ່ມີ VB12, ແລະບໍ່ສາມາດຜະລິດ VB12. ຕັບແມ່ນແຫຼ່ງ VB12 ທີ່ດີທີ່ສຸດ, ຈາກນັ້ນແມ່ນມາຈາກນົມ, ຊີ້ນ, ໄຂ່, ປາແລະອື່ນໆ .VB12 ແມ່ນສານເຄມີທີ່ ຈຳ ເປັນໃນການສັງເຄາະ RNA ແລະ DNA. ການຂາດ VB12 ໃນ vivo ສາມາດເຮັດໃຫ້ເກີດການປ່ຽນແປງທາງດ້ານ pathological ໃນລະບົບປະສາດເຊັ່ນ: ເສັ້ນປະສາດສ່ວນກາງແລະລະບົບປະສາດສ່ວນກາງ.