Vitamin B 12, also known as cobalt amine, is the only vitamin containing metal elements. In nature, vitamin B12 is synthesized by microorganisms. Higher animals and plants cannot make vitamin B12. Vitamin B12 is the only vitamin that requires the help of an intestinal secretion (endogenous factor) to be absorbed. Some people due to gastrointestinal abnormalities, lack of this endogenous factor, even if adequate dietary sources can also suffer from malignant anemia. There is basically no vitamin B12 in vegetable foods. It stays in the gut for a long time and takes about three hours (most water-soluble vitamins take only a few seconds) to be absorbed. Vitamin B 12's main physiological function is to participate in the production of bone marrow red blood cells, prevent malignant anemia, prevent brain nerve damage. Vitamin B 12 is one of the last B vitamins to be found so far. Vitamin B12 is a polycyclic compound containing 3 valent cobalt. Four reduced pyrrole rings are linked together to form a Golin macroring (similar to porphyrin), which is the core of vitamin B12 molecule. Therefore, compounds containing this ring are referred to as Golin-like. Vitamin B12 is a light red acicular crystal which is easily soluble in water and ethanol. It is most stable under the condition of weak acid pH 4.5 and 5.0, and decomposes in strong acid (pH < 2) or alkaline solution, which can be destroyed to some extent in the event of heat. But short time high temperature disinfection loss is small, encounter bright light or ultraviolet ray is easy to be destroyed. The loss of ordinary cooking process is about 30%.

Sunan Samfur:	VITAMIN 12
CAS:	68-19-9
MF:	C63H88CoN14O14P
MW:	1355.37
EINECS:	200-680-0
Vitamin B12, wanda ake kira VB12 a gajarce, wanda aka fi sani da cobalamin, kuma yana daya daga cikin bitamin na B, wani rukuni ne na hadadden mahaukatan mahaukatan da ke dauke da sinadarin cobalt Corrin, kuma suna dauke da sinadarin cobalt mai kama da juna a cikin irin wannan sinadarin na Corrin a tsakiyar zoben. .Wannan shine mafi girman hadadden kwayar bitamin da aka gano. Hakanan shine kawai bitamin tare da ion ƙarfe. Lu'ulu'u ja ne, ana kuma kiransa da jan bitamin. Tsirkan ba shi da VB12, kuma ba zai iya samar da VB12 ba. Hanta ita ce mafi kyawun tushen VB12, sannan daga madara, nama, ƙwai, kifi da sauransu.VB12 muhimmin coenzyme ne a cikin haɗin RNA da DNA. Rashin VB12 a cikin vivo na iya haifar da sauye-sauyen cututtukan cuta a cikin tsarin juyayi kamar jijiyoyin gefe da tsarin juyayi na tsakiya.