Kina Cefotaxime Sodium hale hana a me nā mea hana

ʻO Sodium Cefotaxime

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Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Inoa mea kūʻai	ʻO Sodium Cefotaxime
CAS:	64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
ʻEINECS:	264-915-9
ʻO Cefotaxime (Claforan) ke kolu o nā hanauna hephthospospin e hoʻolauna ʻia. Loaʻa iā ia kahi hana maikaʻibroad-spectrum e kūʻē iā Gram-positive a me Gramnegativeaerobic a me nā koʻohune anaerobic. ʻOi aku ia ma mua o ka moxalactam kūʻē i nā meaola Gram-maikaʻi. ʻO ka nui o nā lactamase – e hana ana i nā ʻano koʻohuna he mea maʻalahi i ka cefotaxime, me N. gonorrhoeae, Klebsiella spp., H. influenzae, S. aureus, a me E. cloacae. Kekahi, akā ʻaʻole naʻe nā mea āpau, maʻalahi nā ʻano Pseudomonas. Kūpaʻa ʻo Enterococci a me Listeriamonocytogenes. ʻOi aku ka nui o ka activist o ka syn-isomer o cefotaxime ma mua o ka anti-isomer e kūʻē i ka bacteria-act-lactamase. ʻo ka syn-isomer no PBPs, eia nō naʻe kekahi kumu. Hoʻopili ʻia ʻo Cefotaxime i kahi ʻāpana i ka desacetylmetabolite hana liʻiliʻi. Ma kahi o 20% o ka metabolite a 25% o ka lāʻau makua i excreted i ka mimi. Hiki i ka lāʻau lapaʻau i ka wai cerebrospinal i lawa ka noʻonoʻo e pono ai i ka mālama ʻana i ka meningitis. Pono e hoʻohana ʻia nā hopena o ka sodium cefotaxime i loko o 24hours Inā mālama ʻia, pono lākou e hoʻomaʻalili ʻia. Mālama i nā ʻōpala i ka pā i ka 10 mau lā.

ʻano hana: penei Penei nā kikoʻī huahana:

Helehelena:	keʻokeʻo a keʻokeʻo paha me kahi ʻōmaʻomaʻo melemele
Solubility:	soluble manuahi i ka wai, soluble sparingly in methanol
Kahi hoʻohuli ʻōnohi kikoʻī:	+58 º ~ +64 º
Pilikino absorbance:	360 ~ 390
Waihoʻoluʻu o ka hopena:	≤0.2
Lilo i ka maloo:	≤3.0%
PH:	4.5 ~ 6.5
ʻIke o cefotaxime:	916μg / mg ~ 964 μg / mg
Pili waiwai:
Hoʻomaʻemaʻe kanaka:	≤1.0%
Huina haumia:	≤3.0%
Hana: ʻO
ʻO Cefotaxime sodium sterile kahi kolu o ka hanauna cephalosporin semi-synthetic me ka hana bactericidal ikaika e kūʻē i nā bacteria maikaʻi ʻole Gram, ʻoi aku ma. ʻO Enterobacter A ʻo Escherichia coli, influenza bacillus, Klebsiella pneumonia, Proteus mirabilis, a me Salmonella, ʻoi aku ka hopena o ka hopena ma mua o Cefoperazone. Hoʻohana ʻia ia no ka maʻi o ka maʻi hanu, ka maʻi urinary, ka iwi a me ka ami, ka ʻili a me nā mea palupalu, ka ʻōpū o ka ʻōpū, nā biliary tract, nā ʻōnaehana digestive, nā helehelena a me nā ʻāpana ʻē aʻe i hoʻokumu ʻia e nā koʻohune maʻalea. He maikaʻi ia no nā maʻi i hoʻokumu ʻia e nā wela a me nā trauma, a me nā sepsis a me nā maʻi o waena.