China Cefotaxime Sodium fakitale ndi opanga

Cefotaxime Sodium

Kufotokozera Kwachidule:

Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Mankhwala Mwatsatanetsatane

Zogulitsa

Dzina lazogulitsa	Cefotaxime Sodium
CAS:	64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
EINECS:	264-915-9
Cefotaxime (Claforan) anali woyamba m'badwo wachitatucephalosporin kuti udziwitsidwe. Ili ndi zochitika zabwino kwambiri zakuthambo motsutsana ndi mabakiteriya a Gram-positive ndi Gramnegativeaerobic ndi anaerobic. Ndi yogwira ntchito moxalactam motsutsana ndi zamoyo za Gram. Mitundu ya bakiteriya yotulutsa manyβ-lactamase imazindikira cefotaxime, kuphatikiza N. gonorrhoeae, Klebsiella spp., H. influenzae, S. aureus, ndi E. cloacae. Ena, koma osati onse, mitundu ya Pseudomonas imazindikira. Enterococci ndi Listeriamonocytogenes amalimbana. Sy-isomer ya cefotaxime imagwira ntchito kwambiri kuposa anti-isomer motsutsana ndi mabakiteriya β-lactamase-opangira. Kusiyana kwamphamvu kumeneku ndi, mwa zina, chifukwa chokana kwambiri kwa syn-isomer pakuchita kwa β-lactamases. syn-isomer ya PBPs, komabe, itha kukhalanso chifukwa. Cefotaxime imagwiritsidwa ntchito moperewera ku desacetylmetabolite. Pafupifupi 20% ya metabolite ndi 25% ya mankhwala a kholo amatulutsidwa mkodzo. Mankhwalawa amabwera ku cerebrospinal madzimadzi okwanira kuti azigwira bwino ntchito ya meningitis.Solution ya cefotaxime sodium iyenera kugwiritsidwa ntchito mkati mwa maola 24. Ngati zasungidwa, ziyenera kukhala m'firiji. Mayankho a mufiriji amasunga potency mpaka masiku 10.

kapangidwe kake: Zambiri zamagetsi ndi izi:

Maonekedwe:	zoyera kapena zoyera ndi ufa wachikasu
Kutha:	sungunuka momasuka m'madzi, sungunuka pang'ono mu methanol
Enieni kuwala kasinthasintha:	+58 º ~ +64 º
Enieni mayamwidwe:	360 ~ 390
Mtundu wa yankho:	.20.2
Kutaya pauma:	.03.0%
PH:	4.5 ~ 6.5
Zofufuza za cefotaxime:	916μg / mg ~ 964 μg / mg
Mankhwala ofanana:
Kusayera payekha:	.01.0%
Kusayera kwathunthu:	.03.0%
Ntchito:
Cefotaxime sodium wosabala ndi mtundu wachitatu wa cephalosporin wokhala ndi bakiteriya wamphamvu wolimbana ndi mabakiteriya a Gram-negative, makamaka pa. Enterobacter. Ponena za Escherichia coli, fuluwenza bacillus, Klebsiella pneumonia, Proteus mirabilis, ndi Salmonella, imathandizira kwambiri kuposa Cefoperazone. Amagwiritsidwa ntchito kupatsira kachilombo koyambitsa matenda, kwamikodzo, mafupa ndi mafupa, khungu ndi zofewa, m'mimba, thirakiti, njira yogaya, nkhope, ziwalo zoberekera ndi zina zomwe zimayambitsidwa ndi mabakiteriya ovuta. Imathandizanso kumatenda omwe amayamba chifukwa chakupsa ndi zoopsa, komanso sepsis ndi matenda apakati.