Saina Cefotaxime Sodium falegaosimea ma gaosi

Cefotaxime Sodium

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Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Oloa Faʻamatalaga

Pine o oloa

Igoa oloa	Cefotaxime Sodium
CAS:	64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
EINECS:	264-915-9
Cefotaxime (Claforan) o le muamua augatupulaga tolu -phagosporin na faʻalauiloaina. O loʻo ia te ia se faʻatinoga lelei tele-faʻapitoa gaioiga faʻasaga i le siama Gram-lelei ma Gramnegativeaerobic ma anaerobic E sili atu activthth moxalactam faasaga i Gram-lelei mea. Tele-lactamase – gaosia siama siama e maaleale i cefotaxime, aofia ai N. gonorrhoeae, Klebsiella spp., H. influenzae, S. aureus, ma E. cloacae. Nisi, ae le o uma, Pseudomonas ituaiga o faʻalavelave e maaleale. Enterococci ma Listeriamonocytogenes e teteʻe. O le syn-isomer o cefotaxime e sili atu ona malosi nai lo le anti-isomer faasaga i le β-lactamase-gaosia siama. O lenei malosiʻaga eseesega, i se vaega, ona o sili atu teteʻe atu o le syn-isomer i le gaioiga o β-lactamases. O le maualuga vavalalata o ole syn-isomer mo PBPs, peitaʻi, e ono avea foʻi ma mafuaʻaga. Cefotaxime e gaosia i se vaega i le laititi gaioiga desacetylmetabolite. E tusa ma le 20% o le metabolite ma le 25% o fualaʻau matua o loʻo faʻateʻaina i le miaga. O vailaʻau oona e aapa atu i le suavai o le cerebrospinal i le lava o le totoga e aoga ai i le togafitia o le fiva faiʻai. A faʻaputu, e tatau ona faʻamamago i totonu o le pusaʻaisa. Faʻamamaina fofo faʻamalosia malosiaga oʻo i le 10 aso.

metotia faʻavae: O auiliiliga o oloa e faʻapea:

Foliga Vaaia:	paʻepaʻe pe papaʻe ma se paʻu samasama samasama efuefu
Solubility:	saoloto soluble i le vai, sparingly soluble i le methanol
Faʻatulagaina faʻasolosolo tipi:	+58 º ~ +64 º
Momo vaʻaia:	360 ~ 390
Lanu o fofo:	≤0.2
Maliu i matutu:	≤3.0%
PH:	4.5 ~ 6.5
Faʻataʻitaʻiga o cefotaxime:	916μg / mg ~ 964 μg / mg
Fesootaiga vailaʻau:
Le mama o le tagata lava ia:	≤1.0%
Aofaʻiga le mama:	≤3.0%
Galuega tauave:
Cefotaxime sodium sterile o le lona tolu o augatupulaga semi-gaosia cephalosporin ma malosi gaioiga siama faʻasaga i Gram-leaga siama, aemaise lava luga. Enterobacter. Ae o le Escherichia coli, fulū bacillus, Klebsiella niumonia, Proteus mirabilis, ma Salmonella, e sili atu lona malosi nai lo Cefoperazone. E faʻaaogaina mo faʻamaʻi o le manava manava, ala urinary, ponaivi ma soʻoga, paʻu ma mea vaivai o le tino, manava manava, biliary tract, digestive tract, foliga foliga, genital ma isi vaega mafua mai maaleale siama. E aoga foi mo faʻamaʻi e mafua mai ile mumu ma manuʻa, faʻapea foʻi sepsis ma faʻamaʻi tutotonu.