Shiinaha Cefotaxime sodium warshad iyo soosaarayaasha

Sodium Cefotaxime

Sharax Gaaban:

Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Calaamadaha alaabta

Magaca badeecada	Sodium Cefotaxime
CAS:	64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
EINECS:	264-915-9
Cefotaxime (Claforan) wuxuu ahaa jiilkii seddexaad ee uguhoreeyay ee la soo bandhigo. Waxay leedahay waxqabad heer sare ah oo caalami ah oo ka dhan ah Gram-positive iyo Gramnegativeaerobic iyo bakteeriyada anaerobic. Way ka firfircoon tahay moxalactam noolaha Gram-positive. Noocyo badan oo bakteeriya soo saaraya ayaa u nugul cefotaxime, oo ay ku jiraan N. gonorrhoeae, Klebsiella spp., H. influenzae, S. aureus, iyo E. cloacae. Qaar, laakiin dhammaantood, noocyada 'Pseudomonas' ayaa xasaasi ah. Enterococci iyo Listeriamonocytogenes waa kuwo iska caabiya. Isku-darka isku-darka 'sefotaxime' wuxuu si aad ah uga firfircoon yahay anti-isomer-ka ka hortagga bakteeriyada β-lactamase. syn-isomer ee PBPs, si kastaba ha noqotee, waxay sidoo kale noqon kartaa cunsur. Cefotaxime waxaa lagu beeray qayb ahaan desacetylmetabolite firfircoon. Qiyaastii 20% ee dheef-shiid kiimikaadka iyo 25% ee daroogada waalidka ayaa laga soo qaadaa kaadida. Daroogada Theparent waxay gaaraan dheecaanka maskaxda ee maskaxda ku filan si ay waxtar ugu yeeshaan daaweynta cudurka meningitis. Haddii la kaydiyo, waa in la qaboojiyaa. Xalka qaboojiyaha hayaa awood ilaa 10 maalmood.

Qaaciddada qaabdhismeedka: Faahfaahinta alaabtu waa sida soo socota:

Muuqaalka:	caddaan ama caddaan leh budo midab jaalle ah
Kala-baxa:	si xor ah ugu milmi kara biyaha, si tartiib ah ugu milma methanol
Wareeg muuqaal gaar ah:	+55 º ~ +64 º
Nuugista Gaarka ah:	360 ~ 390
Midabka xalka:	≤0.2
Loss on qalalan:	≤3.0%
PH:	4.5 ~ 6.5
Tijaabinta cefotaxime:	916μg / mg ~ 964 μg / mg
Maaddada la xidhiidha:
Nijaasta qofka	≤1.0%
Wadarta wasakhda:	≤3.0%
Waxqabadka:
Cefotaxime sodium sterile waa jiil saddexaad oo cephalosporin ah oo isku-dhafan oo leh firfircoonida bakteeriyada ee ka dhanka ah bakteeriyada Gram-negative, gaar ahaan. Bakteeriyada Marka laga hadlayo Escherichia coli, hargabka infalawansada, Klebsiella oof wareenka, Proteus mirabilis, iyo Salmonella, waxay ka saameyn xoog badan tahay Cefoperazone Waxaa loo isticmaalaa infekshinka marinka neef mareenka, marinka kaadi mareenka, lafaha iyo kalagoysyada, maqaarka iyo unugyada jilicsan, daloolka caloosha, marinka biliary, habka dheef shiidka, muuqaalada wajiga, xubnaha taranka iyo qeybaha kale ee ay keento bakteeriyada xasaasiga ah. Waxay sidoo kale waxtar u leedahay infakshannada ay sababaan gubashada iyo naxdinta, iyo sidoo kale sepsis iyo infekshanka dhexe.