China Cefotaxime Sodium masana'anta da masana'antun

Cefotaxime Sodium

Short Bayani:

Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Bayanin Samfura

Alamar samfur

Sunan samfur	Cefotaxime Sodium
CAS:	64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
EINECS:	264-915-9
Cefotaxime (Claforan) shine farkon ƙarni na uku wanda aka gabatar dashi. Yana da kyakkyawan aiki a cikin ƙasa game da Gram-tabbatacce da Gramnegativeaerobic da kwayoyin anaerobic. Ya fi aiki fiye da moxalactam kan ƙwayoyin Gram-tabbatacce. Yawancin nau'ikan-lactamase masu samar da kwayar cuta suna da damuwa ga cefotaxime, gami da N. gonorrhoeae, Klebsiella spp., H. influenzae, S. aureus, da E. cloacae. Wasu, amma ba duka ba, matsalolin Pseudomonas suna da hankali. Enterococci da Listeriamonocytogenes suna da juriya. Syn-isomer na cefotaxime ya fi aiki sosai fiye da anti-isomer akan kwayoyin –-lactamase-samarwa.Wannan bambancin karfin shine, a wani bangare, saboda tsananin karfin sinadarin isomer akan aikin to-lactamases. syn-isomer na PBPs, kodayake, na iya zama mahimmin abu. Cefotaxime yana haɗuwa a wani ɓangare zuwa ƙananan desacetylmetabolite mai aiki. Kusan 20% na metaboliteand 25% na miyagun ƙwayoyi na iyaye an cire su a cikin fitsari. Magunguna masu tsinkaye suna isa cikin kwayar cutar cikin hanzari don yin tasiri wajen magance cutar sankarau. Ya kamata ayi amfani da maganin cefotaxime sodium a cikin 24hours. Idan an adana su, sai a sanyaya su. Abubuwan sanyaya cikin firiji Kula da ƙarfi har zuwa kwanaki 10.

Tsarin tsari: Bayanin samfura kamar haka:

Bayyanar:	fari ko fari tare da hoda mai launin shuɗi
Sauyawa:	mai narkewa cikin ruwa, mai narkewa cikin methanol
Musamman na gani ido:	+58 º ~ +64 º
Takamaiman shayarwa:	360 ~ 390
Launi na bayani:	≤0.2
Asarar akan bushe:	3.0%
PH:	4.5 ~ 6.5
Assay na cefotaxime:	916μg / mg ~ 964 μg / mg
Abubuwa masu dangantaka:
Rashin ɗayan mutum:	≤1.0%
Total ƙazanta:	3.0%
Aiki:
Cefotaxime sodium bakararre shine ƙarni na uku na cephalosporin mai ƙarfi tare da aikin ƙwayoyin cuta mai ƙarfi akan ƙwayoyin cuta na Gram, musamman akan. Kwayar cuta Amma ga Escherichia coli, mura bacillus, Klebsiella ciwon huhu, Proteus mirabilis, da Salmonella, yana da ƙarfi fiye da Cefoperazone. Ana amfani dashi don kamuwa da cututtukan numfashi, urinary tract, kashi da haɗin gwiwa, fata da nama mai laushi, ramin ciki, biliary tract, narkewa kamar abinci, fasalin fuska, al'aura da sauran sassan da ƙananan ƙwayoyin cuta ke haifarwa. Hakanan yana da tasiri ga kamuwa da cuta sakamakon ƙonewa da rauni, da kuma sepsis da kamuwa da cuta ta tsakiya.