China Cefotaxime Sodium fekitori uye vagadziri

Cefotaxime Sodium

Tsananguro Pfupi:

Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Chigadzirwa Chigadzirwa

Chigadzirwa Mateki

Chigadzirwa zita	Cefotaxime Sodium
CAS:	64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
EINECS:	264-915-9
Cefotaxime (Claforan) ndiyo yaive yechitatu-chizvarwacephalosporin kuunzwa. Iyo ine yakanakisa yekuparadzira-sipidhi chiitiko kurwisa Gram-yakanaka uye Gramnegativeaerobic uye anaerobic mabhakitiriya. Iyo inoshanda zvakanyanya kupfuura moxalactam inopesana neGrm-positive zvipenyu. Manyβ-lactamase-inogadzira mabhakitiriya emhando anonzwisisa cefotaxime, kusanganisira N. gonorrhoeae, Klebsiella spp., H. influenzae, S. aureus, uye E. cloacae. Dzimwe, asi kwete dzese, Pseudomonas strains anonzwisisa. Enterococci uye Listeriamonocytogenes zvinopesana. Iyo syn-isomer ye cefotaxime inonyanya kushanda kupfuura iyo anti-isomer kurwisa β-lactamase-inogadzira mabhakitiriya. iyo syn-isomer yePBPs, zvisinei, inogona zvakare kuve chinhu. Cefotaxime inogadziriswa muchikamu kune isingashande desacetylmetabolite. Inenge 20% yemetabolite uye 25% yemushonga wemubereki inoburitswa mumuti. Mushonga weparent unosvika kune cerebrospinal fluid mune yakaringana yevasungwa kuti ibudirire pakurapa meningitis.Solution ye cefotaxime sodium inofanira kushandiswa mukati me24hours. Kana zvakachengetwa, zvinofanirwa kuve firiji. Refrigerated solution inochengetedza potency kusvika kumazuva gumi.

chimiro chechimiro: Chigadzirwa chigadzirwa zvinotevera:

Chitarisiko:	chena kana chena ine yero tinge poda
Simba:	zvakasununguka zvakasununguka mumvura, zvishoma nezvishoma zvakasanganiswa mu methanol
Dzakananga Manyiminya kutenderera:	+58 º ~ +64 º
Yakananga kupinza:	360 ~ 390
Ruvara rwemhinduro:	.20.2
Kurasikirwa pakaoma:	.03.0%
PH:	4.5 ~ 6.5
Ongororo ye cefotaxime:	916μg / mg ~ 964 μg / mg
Chinhu chakafanana:
Kusachena kweumwe neumwe:	.01.0%
Kusachena kwese:	.03.0%
Rinoshanda:
Cefotaxime sodium isina kubereka ndeyechitatu-chizvarwa semi-synthetic cephalosporin ine yakasimba bactericidal chiitiko kurwisa Gram-isina mabhakitiriya, kunyanya pa. Enterobacter. Kana iri Escherichia coli, furuwenza bacillus, Klebsiella pneumonia, Proteus mirabilis, uye Salmonella, ine simba rakasimba kupfuura Cefoperazone. Inoshandiswa kutapukirwa nemhepo yekufema, weti, pfupa uye mubatanidzwa, ganda uye zvinyoro zvinyoro, mudumbu mhango, biliary turakiti, nzira yekugaya, kumeso maficha, nhengo dzesikarudzi uye zvimwe zvikamu zvinokonzerwa nehutachiona husinga nzwisisike. Izvo zvinoshandawo kune hutachiona hunokonzerwa nekutsva uye kushungurudzika, pamwe ne sepsis uye yepakati hutachiona.