China Cefotaxime Sodium mveliso kunye nabenzi

Cefotaxime Sodium

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Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Iimpawu zemveliso

Igama lemveliso	Cefotaxime Sodium
CAS:	Ngowama-64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
IINKCUKACHA:	264-915-9
ICefotaxime (iClaforan) yayisisizukulwana sokuqala sesithathu secephalosporin ukwaziswa. Inomsebenzi obalaseleyo wobubanzi ngokuchasene ne-Gram-positive kunye ne-Gramnegativeaerobic kunye ne-anaerobic bacteria. Isebenza ngakumbi kune-moxalactam ngokuchasene nezinto eziphilayo ze-Gram. Iintlobo ezininzi ze-bacteri-lactamase-ezivelisa iintsholongwane zithambile kwi-cefotaxime, kubandakanya i-N. gonorrhoeae, i-Klebsiella spp., H. influenzae, S. aureus, kunye no-E. cloacae. Ezinye, kodwa ayizizo zonke, iintlobo zePseudomonas ezibuthathaka. I-Enterococci kunye neListeriamonocytogenes ziyamelana. I-syn-isomer ye-cefotaxime isebenza ngakumbi kune-anti-isomer ngokuchasene ne-β-lactamase-evelisa iibhaktheriya. I-syn-isomer ye-PBPs, nangona kunjalo, inokuba nayo yinto. I-Cefotaxime imetabolized kwinxalenye ye-desacetylmetabolite engasebenziyo. Phantse i-20% yemetabolite kunye ne-25% yeziyobisi zomzali ziyakhutshwa kumchamo. Iziyobisi ezingafakwanga zifikelela kulwelo lwe-cerebrospinal kwindawo yoxinaniso eyoneleyo ukuze isebenze kunyango lwe-meningitis.Solutions of cefotaxime sodium should be used within 24hours. Ukuba zigciniwe, kufuneka zifrijiwe. Izisombululo zefriji ukugcina amandla kwiintsuku ezili-10.

Ifomula yolwakhiwo: Iinkcukacha zeMveliso zezi zilandelayo:

Inkangeleko:	umhlophe okanye mhlophe ngomgubo otyheli we-tinge
Ukunyibilika:	inyibilika ngokukhululekileyo emanzini, inyibilike kancinci kwimethanol
Ujikelezo oluthile lokukhanya:	+58 º ~ +64 º
Ukufunxwa ngokukodwa:	360 ~ 390
Umbala wesisombululo:	-0.2
Ilahleko kwindawo eyomileyo:	≤3.0%
PH:	4.5 ~ 6.5
Uvavanyo lwe-cefotaxime:	916μg / mg ~ 964 μg / mg
Izinto ezihambelanayo:
Ukungahlambuluki komntu:	.01.0%
Ukungahlambuluki okupheleleyo:	≤3.0%
Umsebenzi: I-
I-Cefotaxime i-sodium eyinyumba iyisizukulwana sesithathu se-cephalosporin enesenzo esomeleleyo se-bactericidal ngokuchasene ne-bacteria ye-Gram-negative, ngakumbi kwi. Enterobacter. Ngokubhekisele ku-Escherichia coli, influenza bacillus, Klebsiella pneumonia, Proteus mirabilis, kunye neSalmonella, inefuthe elinamandla kuneCefoperazone. Isetyenziselwa usulelo lokuphefumla, umchamo, ithambo kunye nokudibana, ulusu kunye nezicubu ezithambileyo, isisu esiswini, iphecana le-biliary, ithumbu lokugaya, imbonakalo yobuso, amalungu esini kunye namanye amalungu abangelwa ziintsholongwane ezibuthathaka. Kukwayasebenza nosulelo olubangelwa kukutsha kunye ne trauma, kunye ne-sepsis kunye nosulelo oluphambili.