China Cefotaxime Sodium ifektri abakhiqizi

Cefotaxime Sodium

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Product name Cefotaxime Sodium CAS: 64485-93-4 MF: C16H16N5NaO7S2 MW: 477.45 EINECS: 264-915-9 Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrh...

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Imininingwane yomkhiqizo

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Igama lomkhiqizo	Cefotaxime Sodium
CAS:	64485-93-4
MF:	C16H16N5NaO7S2
MW:	477.45
I-EINECS:	264-915-9
ICefotaxime (Claforan) kwaba yisizukulwane sokuqala sesithathu secephalosporin ukwethulwa. Inomsebenzi omuhle kakhulu we-wide-spectrum olwa namagciwane we-Gram-positive ne-Gramnegativeaerobic ne-anaerobic. Isebenza kakhulu kune-moxalactam emelene nezinto eziphilayo ze-Gram. Izinhlobo zamagciwane ezikhiqiza i-manyβ-lactamase ziyazwela ku-cefotaxime, kufaka phakathi uN. Gonorrhoeae, Klebsiella spp., H. influenzae, S. aureus, no-E. cloacae. Ezinye, kepha hhayi zonke, izinhlobo zePseudomonas ziyazwela. I-Enterococci ne-Listeriamonocytogenes ayizweli. I-syn-isomer ye-cefotaxime isebenza kakhulu kune-anti-isomer elwa namagciwane akhiqiza i-β-lactamase –.Lokhu umehluko wamandla, ngokwengxenye, kungenxa yokumelana okukhulu kwe-syn-isomer ekwenzeni kwe-lact-lactamases. i-syn-isomer yama-PBP, noma kunjalo, nayo ingaba yisici. I-Cefotaxime ihlanganiswe ngokwengxenye ne-desacetylmetabolite engasebenzi kangako. Cishe i-20% yemetabolite kanye ne-25% yesidakamizwa sabazali ikhishwe emchameni. Isidakamizwa esingumzali sifinyelela uketshezi lwe-cerebrospinal ekugxileni okwanele ukuze lusebenze ekwelapheni i-meningitis.Izixazululo ze-cefotaxime sodium kufanele zisetshenziswe kungakapheli amahora angama-24. Uma zigciniwe, kufanele zifakwe esiqandisini. Izixazululo eziqandisiwe zigcina amandla kuze kube yizinsuku eziyi-10.

ifomula lesakhiwo: Imininingwane yomkhiqizo imi kanjena:

Ukubukeka:	mhlophe noma mhlophe ngempuphu ye-tinge ephuzi
Umswakama:	incibilika ngokukhululeka emanzini, incibilike kancane emethanoli
Ukujikeleza okukhethekile okubonakalayo:	+58 º ~ +64 º
Ukumunca okuqondile:	360 ~ 390
Umbala wesixazululo:	.20.2
Ukulahlekelwa komile:	≤3.0%
PH:	4.5 ~ 6.5
Ukuhlolwa kwe-cefotaxime:	916μg / mg ~ 964 μg / mg
Into ehlobene:
Ukungcola komuntu ngamunye:	≤1.0%
Ukungcola okuphelele:	≤3.0%
Umsebenzi: I-
I-Cefotaxime i-sodium oyinyumba iyi-cephalosporin yesizukulwane sesithathu enomsebenzi oqinile wama-bactericidal alwa namagciwane we-Gram-negative, ikakhulukazi. I-Enterobacter. Ngokuqondene ne-Escherichia coli, i-influenza bacillus, i-Klebsiella pneumonia, i-Proteus mirabilis, ne-Salmonella, inamandla amakhulu kune- Cefoperazone. Isetshenziselwa ukutheleleka ngomgudu wokuphefumula, umgudu wokuchama, ithambo nokuhlangana, isikhumba nezicubu ezithambile, umgodi wesisu, umgudu we-biliary, umgudu wokugaya ukudla, ubuso bobuso, izitho zangasese nezinye izingxenye ezibangelwa amagciwane abucayi. Kuyasebenza futhi ezifweni ezibangelwa ukusha nokuhlukumezeka, kanye ne-sepsis nokutheleleka okuphakathi.