Benzylpenicillin potaziyamu imakhala ndi antibacterial yabwino pa streptococcus, streptococcus pneumoniae ndi staphylococcus zomwe sizipanga enzyme ya penicillin. Ili ndi zochita zolimbana ndi mabakiteriya zolimbitsa thupi. Neisseria gonorrhoeae, neisseria meningitidis, corynebacterium diphtheriae, bacillus anthracis, actinomyces bovis, streptococcus candida, listeria listeriae, leptospira ndi treponema pallidum amazindikira izi. Chida ichi chimakhalanso ndi ma antibacterial anti-haemophilus influenzae ndi bordetella pertussis. Ma grobe-negative aerobe kapena ma anaerobe osazindikira sazindikira izi. Chida ichi chimakhala ndi antibacterial zotsatira zabwino pa clostridium, anaerobe ya digestive streptococcus ndi bacillus .