China Cefoperazone Sodium factory and manufacturers

Cefoperazone Sodium

Short Description:

Product name Cefoperazone sodium CAS: 62893-20-3 MF: C25H26N9NaO8S2 MW: 667.65 Cefoperazone sodium is a third-generation, antipseudomonalcephalosporin that resembles piperacillinchemically and microbiologically. It is active against manystrains of P. aeruginosa, indole-positive Proteus spp.,Enterobacter spp., and S. marcescens that are resistant tocefamandole. It is less active than cephalothin againstGram-positive bacteria and less active than cefamandoleagainst most of the En...

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Product name	Cefoperazone sodium
CAS:	62893-20-3
MF:	C25H26N9NaO8S2
MW:	667.65
Cefoperazone sodium is a third-generation, antipseudomonalcephalosporin that resembles piperacillinchemically and microbiologically. It is active against manystrains of P. aeruginosa, indole-positive Proteus spp.,Enterobacter spp., and S. marcescens that are resistant tocefamandole. It is less active than cephalothin againstGram-positive bacteria and less active than cefamandoleagainst most of the Enterobacteriaceae. Like piperacillin,cefoperazone is hydrolyzed by many of the β-lactamasesthat hydrolyze penicillins. Unlike piperacillin, however, itis resistant to some (but not all) of the β-lactamases thathydrolyze cephalosporins.Cefoperazone is excreted primarily in the bile. Hepaticdysfunction can affect its clearance from the body.

Product details are as follows:

Specific optical rotation:	-155~ -170º
Water:	8.0%-11.0%
Colour of solution:	≤ Y5 or BY5
Bacterial endotoxin:	<0.08EU/mg
PH:	6.0~8.0
Assay :	≥98%
Total impurity:	≤4.0%
Function:
cefoperazone sodium is a third-generation semi-synthetic cephalosporin with strong bactericidal activity against Gram-negative bacteria, especially on. Enterobacter. As for Escherichia coli, influenza bacillus, Klebsiella pneumonia, Proteus mirabilis, and Salmonella, it has stronger effect than Cefoperazone. It is used for infection of respiratory tract, urinary tract, bone and joint, skin and soft tissue, abdominal cavity, biliary tract, digestive tract, facial features, genitals and other parts caused by sensitive bacteria. It is also effective for infections caused by burns and trauma, as well as sepsis and central infection.