I-Metronidazole: I-Antibiotic eneMisebenzi eBanzi

I-Metronidazole, i-antibiotic esekelwe kwi-nitroimidazole kunye nomsebenzi womlomo, iye yavela njengeyona nto ibalulekileyo yonyango ekunyangeni uluhlu olubanzi lwezifo. Eyaziwa ngokuba namandla okungena kumqobo wegazi-ingqondo, eli chiza libonise ukusebenza okumangalisayo ekujonganeni neemeko zonyango ezahlukeneyo.

I-Metronidazole isebenza ngokukodwa ngokuchasene ne-anaerobic microorganisms. Ibonisa umsebenzi wokuthintela ngokuchasene ne-anaerobic protozoa efana ne-Trichomonas vaginalis (ebangela i-trichomoniasis), i-Entamoeba histolytica (ejongene ne-amoebic dysentery), i-Giardia lamblia (ebangela i-giardiasis), kunye ne-Balantidium coli. Izifundo ze-in vitro zibonise umsebenzi wayo we-bactericidal ngokuchasene neebhaktheriya ze-anaerobic ekugxininiseni kwe-4-8 μg / mL.

Kwicandelo lezonyango, i-Metronidazole imiselwe unyango lwe-trichomoniasis yangasese, izifo ze-amoebic zamathumbu kunye neendawo zangaphandle, kunye ne-leshmaniasis yesikhumba. Ikwasebenza ekulawuleni ezinye izifo ezifana ne-sepsis, i-endocarditis, i-empyema, amathumba emiphungeni, usulelo lwesisu, usulelo lwe-pelvic, usulelo lwe-gynecological, usulelo lwethambo kunye noludibeneyo, i-meningitis, amathumba ebuchotsheni, ulusu kunye nosulelo lwezicubu ezithambileyo, i-pseudomembranous colitis, i-Helicobacter-associated pyloptic gastric.

Ngaphandle kweenzuzo zayo zonyango, iMetronidazole inokubangela ukusabela okungalunganga kwezinye izigulana. Ukuphazamiseka kwesisu okuqhelekileyo kubandakanya isicaphucaphu, ukuhlanza, i-anorexia, kunye neentlungu zesisu. Iimpawu ze-neurological ezifana nentloko, isiyezi, kunye nokuphazamiseka kweemvakalelo ngamanye amaxesha kunye ne-neuropathies ezininzi zinokuthi zenzeke. Kwiimeko ezinqabileyo, izigulana zingafumana irhashalala, ukugungxulwa, ukurhawuzelela, icystitis, ubunzima bokuchama, incasa yesinyithi emlonyeni, kunye neleukopenia.

Iingcali zempilo zigxininisa ukubaluleka kokubeka iliso kwizigulane ngokusondeleyo ngexesha lonyango lweMetronidazole ukuqinisekisa ukhuseleko kunye nokusebenza kakuhle. Ngomsebenzi wayo obanzi kunye nokusebenza kakuhle okusekiweyo, iMetronidazole iyaqhubeka nokuba yinto exabisekileyo kwi-arsenal antimicrobial.