Metronidazole: Antibiyotike itandukanye hamwe na porogaramu nini

Metronidazole, antibiyotike ishingiye kuri nitroimidazole ifite ibikorwa byo mu kanwa, yagaragaye nk'umuti w'ingenzi mu kuvura indwara zitandukanye. Uyu muti uzwiho ubushobozi bwo kwinjira mu nzitizi y’amaraso-ubwonko, uyu muti wagaragaje imbaraga zidasanzwe mu gukemura ibibazo bitandukanye by’ubuvuzi.

Metronidazole ifite akamaro kanini kurwanya mikorobe ya anaerobic. Irerekana ibikorwa byo kubuza kurwanya anaerobic protozoa nka Trichomonas vaginalis (itera trichomoniasis), Entamoeba histolytica (ishinzwe indwara ya amoebic dysentery), Giardia lamblia (itera giardiasis), na Balantidium coli. Mu bushakashatsi bwa vitro bwerekanye ibikorwa byabwo byica bagiteri kurwanya bagiteri ya anaerobic kuri 4-8 μg / mL.

Mu rwego rw'ubuvuzi, Metronidazole yandikiwe kuvura trichomoniasis yo mu gitsina, indwara za amibe zo mu mara no mu nda, hamwe na leshmaniyasi y'uruhu. Ifite kandi akamaro mu gucunga izindi ndwara nka sepsis, endocarditis, empyema, ibisebe by ibihaha, kwandura mu nda, kwandura pelvic, kwandura indwara z’abagore, kwandura amagufwa hamwe n’indwara zifata ingingo, meningite, ibibyimba byo mu bwonko, uruhu n’indwara zoroshye, indwara ya pisudomembranous colitis, Helicobacter pylori ifitanye isano na gastrite, cyangwa ibisebe bya peptike.

Nubwo bifite akamaro ko kuvura, Metronidazole irashobora gutera ingaruka mbi kubarwayi bamwe. Guhungabana kwa gastrointestinal harimo isesemi, kuruka, anorexia, no kubabara munda. Ibimenyetso byubwonko nko kubabara umutwe, kuzunguruka, hamwe rimwe na rimwe guhungabana kwumva hamwe na neuropathies nyinshi nabyo bishobora kubaho. Mubihe bidasanzwe, abarwayi barashobora guhura nigisebe, guhindagurika, pruritus, cystite, ingorane zo kwihagarika, uburyohe bwumunwa mukanwa, na leukopenia.

Inzobere mu by'ubuzima zishimangira akamaro ko gukurikiranira hafi abarwayi mu gihe cyo kuvura Metronidazole kugira ngo umutekano urusheho kugenda neza. Hamwe nibikorwa byinshi kandi byashizweho neza, Metronidazole ikomeje kuba inyongera yingirakamaro kuri arsenal ya mikorobe.