Metronidazole: Antibiotic Yosiyanasiyana Yokhala ndi Ntchito Zambiri

Metronidazole, mankhwala opangidwa ndi nitroimidazole omwe amagwira ntchito pakamwa, adawonekera ngati chida chofunikira kwambiri pochiza matenda osiyanasiyana. Mankhwalawa amadziwika kuti amatha kulowa m'magazi a ubongo, ndipo awonetsa mphamvu zake pothana ndi matenda osiyanasiyana.

Metronidazole ndi yothandiza kwambiri polimbana ndi tizilombo toyambitsa matenda. Imawonetsa zoletsa zolimbana ndi anaerobic protozoa monga Trichomonas vaginalis (kuyambitsa trichomoniasis), Entamoeba histolytica (yomwe imayambitsa kamwazi ya amoebic), Giardia lamblia (kuyambitsa giardiasis), ndi Balantidium coli. Kafukufuku wa in vitro awonetsa ntchito yake ya bactericidal motsutsana ndi mabakiteriya a anaerobic pamlingo wa 4-8 μg/mL.

Mu zachipatala, Metronidazole analamula zochizira nyini trichomoniasis, amoebic matenda a intestine ndi extraintestinal malo, ndi khungu leshmaniasis. Ndiwothandizanso pakuthana ndi matenda ena monga sepsis, endocarditis, empyema, zilonda zam'mapapo, matenda am'mimba, matenda am'mimba, matenda am'mimba, matenda am'mafupa ndi olowa, meningitis, abscesses muubongo, matenda akhungu ndi zofewa, pseudomembranous colitis, Helicobacter-associates pyloptic gastroenteritis.

Ngakhale kuti mankhwalawa ndi othandiza, Metronidazole imatha kuyambitsa zovuta zina mwa odwala. Kusokonezeka kwa m'mimba kawirikawiri kumaphatikizapo nseru, kusanza, anorexia, ndi kupweteka kwa m'mimba. Zizindikiro zaubongo monga mutu, chizungulire, komanso nthawi zina kusokonezeka kwamalingaliro ndi ma neuropathies angapo amathanso kuchitika. Nthawi zina, odwala amatha zidzolo, totupa, pruritus, cystitis, vuto pokodza, zitsulo kulawa mkamwa, leukopenia.

Ogwira ntchito zachipatala amatsindika kufunika koyang'anira odwala mosamala panthawi ya chithandizo cha Metronidazole kuti atsimikizire chitetezo ndi mphamvu. Chifukwa cha kuchuluka kwa zochita zake komanso mphamvu zake, Metronidazole ikupitilizabe kukhala chowonjezera pagulu lankhondo la antimicrobial.