l: He lāʻau antibiotic maʻamau no nā noi like ʻole

I loko o ke aupuni o nā lāʻau'alopelo, ua puka mai ka Oxytetracycline HCl ma ke ʻano he pūhui pivotal ma muli o kāna mau waiwai antibacterial ākea ākea a me ka versatility i nā noi like ʻole. I kēia mau lā, ua loaʻa i kēia pūhui ka manaʻo nui mai nā kaiāulu ʻepekema a me nā ʻoihana ʻoihana, e lilo ia i kumuhana no ka noiʻi ikaika a me ka hoihoi pāʻoihana.

ʻO ka Oxytetracycline HCl, me kāna ʻano kemika C22H24N2O9·HCl a me ke kaumaha molekala o 496.89, he pauda crystalline melemele i paʻa i ka lewa akā hiki ke pōʻeleʻele ma lalo o ka ʻike ʻana i ka lā. Aia kēia antibiotic i ka papa tetracycline o nā lāʻau lapaʻau a me nā hana ma ke kāohi ʻana i ka synthesis protein ma o ka pale ʻana i ka hoʻopaʻa ʻana o aminoacyl-tRNA i ka subunit ribosomal 30S. Hoʻopili ʻia kāna hana ākea ākea i ka bacteria Gram-positive a me Gram-negative, e lilo ia i mea hana waiwai i ka noiʻi a me nā noi hana.

ʻIke ʻia ka lāʻau antibiotic no kona pono i nā ʻano ʻano olakino holoholona like ʻole. Ua noiʻi ʻia kahi haʻawina i paʻi ʻia ma ka Poultry Science i ka makahiki 1977 i ka pharmacodynamics o ka oxytetracycline HCl i loko o nā moa. Ua ʻike ʻia ka noiʻi ʻana he maikaʻi nā ala o ka waha a me ka intramuscular, me nā ala intramuscular a me nā ala subcutaneous e hopena i nā pae kiʻekiʻe. ʻO ka mea nui, loaʻa nā kiʻekiʻe kiʻekiʻe o ka lāʻau lapaʻau i nā ʻāʻī a me ke akepaʻa, ʻoiai he haʻahaʻa ka nui o ka māmā a me ka serum. Hōʻike kēia noiʻi i ke koʻikoʻi o nā ala hoʻokele kūpono i ka hōʻoia ʻana i ka lawe ʻana i ka lāʻau lapaʻau.

Ma waho aʻe o kāna mau noi olakino holoholona, ​​hoʻohana nui ʻia ʻo Oxytetracycline HCl i ka meaʻai mahiʻai e hāpai i ka ulu ʻana a pale i nā maʻi. No ka laʻana, i ka hānai puaʻa, hoʻohana ʻia ma nā ʻano kikoʻī e pili ana i ka makahiki o nā puaʻa. Pēlā nō, i ka hānai moa, ua hoʻohui ʻia e hoʻonui i ka ulu a me ke olakino, ʻoiai me nā kaohi i ka wā o ka waiho ʻana. Hōʻike kēia mau noi i ka pono a me ka versatility o ka hui i ka mahi holoholona.

Ua hoʻonui nui ʻia ka hana ʻoihana a me ka loaʻa pāʻoihana o Oxytetracycline HCl. Hāʻawi kekahi mau hui, e like me Shanghai Zeye Biotechnology Co., Ltd., i kēia huahana i nā kikoʻī a me nā nui. Mālama kēia mau hui i nā pae maʻemaʻe kiʻekiʻe, ʻoi aku ma mua o 95% (HPLC), a hāʻawi i nā kikoʻī kikoʻī o nā huahana, me nā helu CAS, nā paona molekala, a me nā kūlana mālama. Me nā hana i hoʻokumu ʻia i ka noiʻi a me ka hoʻomohala ʻana, hoʻoikaika mau kēia mau ʻoihana e hoʻomaikaʻi i ka maikaʻi o ka huahana a hoʻonui i kā lākou laina huahana e hoʻokō i nā koi o ka mākeke.

ʻO ka hoʻonui ʻana i ka ʻoihana kūʻai o Oxytetracycline HCl ua hoʻoikaika pū i ka noiʻi i kāna mau noi kūpono ma mua o ka hoʻohana kuʻuna. I ka noiʻi biochemical, lilo ka pūhui i mea hana waiwai no ke aʻo ʻana i ka synthesis protein a me ka hana ribosomal. ʻO kona hiki ke kuhikuhi pono i nā subunits ribosomal bacteria e lilo ia i moho maikaʻi no ka hoʻomohala hou ʻana i ke kahua o ka ʻike lāʻau antibacterial.

Eia kekahi, ʻo ka hoʻohana ʻana o Oxytetracycline HCl i nā hoʻokolohua electrophoresis e hōʻike ana i kona noi ʻana i ka noiʻi biology molecular. ʻO kāna mau pilina kikoʻī me ka DNA a me ka electrophoresis buffers e lilo ia i mea hoʻoponopono pono no ke aʻo ʻana i nā hiʻohiʻona neʻe DNA a me nā hoʻokumu ʻana. Hāʻawi kēia mau haʻawina i ka hoʻonui ʻana i ko mākou ʻike i nā mīkini molekala a hoʻomaʻamaʻa i ka hoʻomohala ʻana i nā ʻenehana diagnostic hou.

I ka hopena, kū ʻo Oxytetracycline HCl ma ke ʻano he hōʻike i ka hoʻomau ʻana o ka ulu ʻana a me ka holomua o ka ʻenehana antibiotic. ʻO kāna hana antibacterial ākea ākea, i hui pū ʻia me kāna versatility i nā noi like ʻole, e hōʻike ana i kona koʻikoʻi i ka noiʻi a me nā hoʻonohonoho pono. Ke hoʻomau nei nā ʻoihana i ka hoʻonui ʻana i nā ʻano hana a me ka hoʻonui ʻana i nā makana huahana, e ulu paha nā noi kūpono o Oxytetracycline HCl, e hoʻopaʻa hou ana i kona kūlana ma ke ʻano he pōhaku kihi i ke kahua o nā lāʻau antibiotic.