Metronidazole: He Antibiotic Versatile me nā noi ākea

Metronidazole, he nitroimidazole-based antibiotic me ka hana waha, ua puka mai ma ke ʻano he lāʻau lapaʻau koʻikoʻi i ka mālama ʻana i nā ʻano maʻi ākea. ʻIke ʻia no kona hiki ke komo i ka pale koko-lolo, ua hōʻike kēia lāʻau lapaʻau i ka maikaʻi kupaianaha i ka hoʻoponopono ʻana i nā kūlana olakino.

ʻO ka metronidazole ka mea kūpono e kū'ē i nā microorganism anaerobic. Hōʻike ʻo ia i ka hana pale ʻana i nā protozoa anaerobic e like me Trichomonas vaginalis (ke kumu trichomoniasis), Entamoeba histolytica (ke kuleana no ka amoebic dysentery), Giardia lamblia (ke kumu o ka giardiasis), a me Balantidium coli. Ua hōʻike ʻia nā haʻawina in vitro i kāna hana bactericidal e kūʻē i ka bacteria anaerobic ma ka nui o 4-8 μg/mL.

I ka lāʻau lapaʻau, ua kuhikuhi ʻia ʻo Metronidazole no ka mālama ʻana i ka trichomoniasis vaginal, nā maʻi amoebic o ka ʻōpū a me nā pūnaewele extraintestinal, a me ka leshmaniasis ʻili. He mea maikaʻi hoʻi ia i ka mālama ʻana i nā maʻi ʻē aʻe e like me sepsis, endocarditis, empyema, lung abscesses, abdominal maʻi, pelvic maʻi, gynecological maʻi, iwi a me nā maʻi hui, maningitis, lolo abscesses, ʻili a me nā maʻi palupalu palupalu, pseudomembranous colitis, Helicobacter pylori-associated gastritis.

ʻOiai nā pōmaikaʻi therapeutic, hiki i ka Metronidazole ke hana i nā hopena ʻino i kekahi mau maʻi. ʻO nā pilikia o ka ʻōpū maʻamau e pili ana i ka nausea, ka luaʻi, ka anorexia, a me ka ʻeha ʻōpū. ʻO nā hōʻailona neurological e like me ke poʻo poʻo, ka noʻonoʻo, a i kekahi manawa hiki ke hoʻopilikia i ka naʻau a me nā neuropathy he nui. I nā hihia kakaʻikahi, hiki i nā maʻi ke loaʻa i ka ʻūhū, ka ʻulaʻula, ka ʻuʻuku, ka cystitis, ka paʻakikī o ka mimi ʻana, ka ʻono metala ma ka waha, a me ka leukopenia.

Hoʻomaopopo ka poʻe ʻoihana mālama ola i ke koʻikoʻi o ka nānā ʻana i nā mea maʻi i ka wā o ka mālama ʻana iā Metronidazole e hōʻoia i ka palekana a me ka pono. Me kāna ākea ākea o ka hana a me ka hoʻokumu ʻana i ka pono, ke hoʻomau nei ʻo Metronidazole i mea waiwai nui i ka antimicrobial arsenal.