Metronidazole: Kwayoyin Kwayoyin Kwayoyin cuta masu Yaduwa tare da Manyan Aikace-aikace

Metronidazole, maganin rigakafi na tushen nitroimidazole tare da aikin baka, ya fito a matsayin mahimmin maganin warkewa wajen magance cututtuka masu yawa. Sanin ikonsa na shiga shingen kwakwalwar jini-kwakwalwa, wannan magani ya nuna matukar tasiri wajen magance yanayin kiwon lafiya daban-daban.

Metronidazole yana da tasiri musamman a kan kwayoyin anaerobic. Yana nuna ayyukan hanawa akan protozoa anaerobic irin su Trichomonas vaginalis (wanda ke haifar da trichomoniasis), Entamoeba histolytica (mai alhakin dysentery amoebic), Giardia lamblia (wanda ke haifar da giardiasis), da Balantidium coli. Nazarin in vitro ya nuna ayyukansa na ƙwayoyin cuta akan ƙwayoyin cuta anaerobic a yawan adadin 4-8 μg/mL.

A fannin likitanci, an wajabta Metronidazole don maganin trichomoniasis na farji, cututtukan amoebic na hanji da wuraren waje, da leshmaniasis na fata. Har ila yau yana da tasiri wajen sarrafa wasu cututtuka irin su sepsis, endocarditis, empyema, huhu abscesses, ciwon ciki, cututtuka na pelvic, cututtuka na gynecological, cututtuka na kashi da haɗin gwiwa, ciwon sankarau, ciwon kwakwalwa, cututtuka na fata da taushi nama, pseudomembranous colitis, Helicobacter pylori-maganin ulcers, gastritis.

Duk da fa'idodin warkewa, Metronidazole na iya haifar da mummunan halayen a wasu marasa lafiya. Abubuwan da ke tattare da hanji sun haɗa da tashin zuciya, amai, anorexia, da ciwon ciki. Alamun jijiya irin su ciwon kai, dizziness, da damuwa na lokaci-lokaci da kuma neuropathies da yawa na iya faruwa. A lokuta da yawa, marasa lafiya na iya samun kurji, flushing, pruritus, cystitis, wahalar fitsari, ɗanɗanon ƙarfe a baki, da leukopenia.

Ma'aikatan kiwon lafiya sun jaddada mahimmancin kulawa da marasa lafiya a hankali yayin maganin Metronidazole don tabbatar da aminci da inganci. Tare da faffadan aikin sa da ingantaccen ingancinsa, Metronidazole yana ci gaba da zama ƙari mai mahimmanci ga arsenal na antimicrobial.